Tuesday, July 7, 2015

Wrap Up

I wanted to do a post to wrap this blog up.

After the miscarriage last fall we were losing hope. We started looking into adoption seriously but decided to talk to one more doctor and do a round of donor IUI or if that was not possible do donor sperm.

We started talking to the new doctor in January and more tests were ordered. An advanced semen analysis and a DNA fragmentation.  The Semen analysis came back at a count of 800,000 38% motility, 1% normal morphology, with major defects. The DNA fragmentation came back at borderline.  That was done on 2/23.  On 2/26 we went out of town.  On 3/10 I found out I was pregnant.

Today I am 21 weeks and 1 day pregnant today with our little girl. So far she is healthy and growing on plan!  If you want to follow the pregnancy progress check out my new blog, 40, Fat and Pregnant

Thursday, September 4, 2014

Tequila Rose

Life is what happens when you are making other plans.

We decided to take a short break from medications and procedures and go on vacation.   I was kind of annoyed because my period was due the last day of our vacation. Well, it didn't start that day, or the next day, or the next day.  Two days after we got back from vacation (this past Monday) I took a pregnancy test and it was positive. So I took 3 more, all positive including a digital.
 


We were excited and scared and freaked out. It was amazing that his had happened. After all of these procedures and medications and time and money, this had happened naturally, out of the blue.  It was a holiday but I called the doctor anyway and he ordered a blood test. I joked that we'd name our daughter Tequila since she was likely conceived on our vacation in Mexico. 

I went and had the test but didn't hear back until Tuesday morning. Tuesday morning I took another test and it was lighter, which indicated to me that something was wrong, it should have been getting darker.  I got the call later that morning, the numbers came back low. My HCG was 25 and my progesterone 10.9.  They put me on Progesterone in Oil shots and scheduled more blood work for Wednesday (today).  

I had the test today and got the call, HCG has dropped to 9 and progesterone was up to 18.8 from the supplements.  

I'm in the process of miscarrying the pregnancy.  I barely even knew it existed and now its going to be gone.  I'm trying to look on the bright side that we went from completely infertile to a natural pregnancy.  That is really amazing.

Digital tests require an HCG of 50 to register pregnant but later that same day a blood test showed 25 and 48 hours later 9, that is a pretty fast drop.
Based on my last period I am 4 weeks and 4 days pregnant today.

I was taking 200mg oral progesterone from 10dpo. Yesterday added 50mg progesterone in oil injection and 2 100mg endometrium suppositories. I'm supposed to stop all progesterone and wait for my period to start.

It's been a rollercoaster ride of emotions this week.

Tuesday, June 24, 2014

IUI Cost

So far, IUI #1 cost about $640 and IUI#2 cost $670.   So far my insurance has been paying for my ultrasounds all but $30 which is great this cost is for medications, ultrasounds and procedure.

IUI #2

Had IUI #2 today.

My ovulation predictor was positive on Sunday.   I went in yesterday for an ultrasound and had a follicle on my left.  Since he is trying to lengthen my leuetal phase he had me do an injection of 2,500 iu of HCG yesterday. I'll do another on Wednesday, a third on Friday and the last on Sunday.   On Friday I will also start Endometrium, a progesterone suppository.

The sperm was not nearly as good today.  There were very few motile, he let me look in the microscope.  He made sure I knew how small the chances of success were before he did the IUI.

Since I'm on the HCG a home pregnancy test won't work (would be false positive) until 5 days at least after my last injection.

I'm not going to get my hopes up this cycle like I did  last time.

Thursday, June 19, 2014

This month's cycle

When I went in for my last ultrasound he found a cyst, which is basically when a follicle does not collapse after a cycle. They usually continue to grow and can become painful until they are either reabsorbed or in my case usually burst.

When you have a cyst they can't put you on Clomid because the cyst can become dangerously large. So I was instructed to get a blood draw on CD10 (yesterday) to check my estrogen level. It came back at 134. That's about the same level it as last time I had a cyst.  I had some sharp pains yesterday and figured the cyst had burst. He had me come in for an ultrasound today and confirmed that there was free fluid, indicating the cyst had burst.

I have 3 follicles now, 2 on the right and one of the left.  We will not be doing Clomid this cycle because of it being so late in the cycle. We might be able to do an IUI anyway though, depending on if the follicles mature properly.  I go back on Monday morning for another ultrasound.

Oh and there were 3 people in the room today staring at my crotch during my ultrasound. Doctor, intern and nurse. It's a good thing I'm not modest.

Tuesday, June 10, 2014

The Fat Lady Sang

This IUI cycle is over, the fat lady sang yesterday.

I go into the doctor for an ultrasound on Friday to make sure all of the follies from this cycle emptied before starting meds for a new cycle.  We also will be discussing timing this cycle a little more closely as it may have been about 12-24 hours too late this time.

Monday, June 9, 2014

Some lessons and the signs

So a couple of biology/anatomy/physiology lessons before today's update.

More about the IUI process
During an IUI the washed semen is placed, using a catheter directly into the uterus, bypassing the cervix.  The timing of this is critical.  The sperm needs to be waiting for the egg when its ovulated from the ovary but washed sperm has a much shorter life than raw sperm, 12-24 hours as opposed to the 3-5 days of raw sperm.   The woman has an ultrasound which measures the size of the follicles in the ovaries and determines if they are large enough to induce ovulation.  Typically doctors want the follicles to be around 20mm before triggering.  The trigger is a 10,000iu shot of HCG which quickly finishes the egg maturation process and incites a "forceful" ovulation.   The HCG shot is normally given 24-36 hours before the IUI procedure.

Basal Body Temperature Tracking
Basal body temperature (BBT) is the lowest body temperature attained while at rest (usually sleep).  A woman's basal body temperature fluctuates in a predictable pattern throughout the course of her menstrual cycle.  Many women track BBT as a way to pinpoint ovulation and predict the onset of their period.   At the beginning of a cycle the temperature is typically low, usually rising slowly up to the point of ovulation where it drops down usually for one or two days before making a quick rise.  These changes are triggered by hormones, the surge of luteinizing hormone (LH) at ovulation causes the drop and then the rise of progesterone after ovulation keeps the temperature high.  The body temperature usually starts to drop a couple of days before the onset of the period.  If pregnancy occurs the temperature remains high.

The Two Week Wait (2WW  or TWW)
Trying to conceive (TTC) is all about the 2 week wait. Its called a 2 weeks wait even though it can be slightly less or slightly more.  Each woman cycle varies slightly in length and can vary from cycle to cycle.  The cycle is broken down into 4 parts, the follicular phase where the ovaries are maturing an egg (or multiple eggs if on fertility drugs), ovulation where the ovaries release the egg, the leuetal phase where if an egg is fertilized it will start to become an embryo and implant into the uterus and menstruation.   The IUI procedure starts the two week wait and marks the beginning of the leuetal phase.  In most women the leuetal phase is about 14 days.  During that two weeks if the egg is fertilized then a lot is going on.  HCG, which is what is measured by a home pregnancy test is not produced by the body until after implantation.  Once implantation occurs then HCG is produced and the amount doubles approximately every 48 hours.   It typically takes about 4-5 days after implantation for the amount of HCG to reach a level it can be measured on a home pregnancy test.



The update
So now that you've had your lesson of the day here is what's going on with me.  My leuetal phase is typically 12 days long.  Today is day 12 for me.  I took a home pregnancy test yesterday and it was negative and my body temperature had dropped for the past two days.  Both of these things indicate that we are likely out (not pregnant) this cycle. It is of course not over until the fat lady sings but all biological signs point to that being the case.